Difference Between Antibody and Antigen

Difference between antibody and antigen testAntigens and antibodies are two very different things. Briefly, an antibody is a glycoprotein produced in response to and in response to a specific antigen. An antigen, on the other hand, is a foreign (usually harmful) substance that triggers an immune response, thus stimulating the production of antibodies.

What is Antibody?

An antibody is produced by your immune system after your body senses a foreign object. When your immune system recognizes a virus, bacteria, allergen, or other substance, it produces proteins (antibodies) to block the same substances the next time you encounter them.2

What is Antigen?

An antigen is a toxic foreign substance that your immune system recognizes as absent from your body. Antigens can be viruses, allergens, and even drugs, causing the body to build an immune system to fight disease or infection. Antigens are required to start the antibody production process.1

Difference Between Antibody and Antigen



Also called

Also called Immunogens Also called Immunoglobulins

Molecular Type

Antigens are usually lipids. However, they can also be proteins, carbohydrates and nucleic acids All antibodies are proteins


Antigens cause allergic reactions or even illnesses Protects against the effects of the antigen either by lysis or immobilization of the particle

Specific Binding Site

Epitopes are regions of the antigen where interacts with the antibodies Paratopes are variable regions of an antibody that binds to an epitope.


Antigens have origins outside the body Antibodies always originate within the body


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