Difference Between Deoxyribose And Ribose

Ribose and deoxyribose are monosaccharides or simple sugars. These are aldopentoses and are phosphorylated to form deoxyribonucleotides and ribonucleotides. They have great biological significance in helping to create an organism that is passed down through generations.

Nucleotides act as building blocks for nucleic acids and help them transmit genetic information. For RNA, the pentose sugar is ribose with 5 carbon atoms. For DNA, the pentose sugar is deoxyribose.

Difference Between Deoxyribose And Ribose

Ribose was discovered by Emil Fischer and Oscar Piloti in 1891. Deoxyribose was discovered by Phoebus Levene in 1929. Some differences between deoxyribose and ribose based on structure, IUPAC name, foot mass, chemical structure, etc. are given below.

What is Ribose?

Ribose is a simple sugar with carbon 5. This sugar molecule has the chemical formula H−(C=O)−(CHOH)4−H. It is an essential part of ribonucleic acid strands. It makes ribonucleotides.

These ribonucleotides are required for encoding, decoding, and regulation of gene expression. It is a simple monosaccharide or sugar that acts as a basic component to form RNA clusters.

What is Deoxyribose?

And your monosaccharide deoxyribose. It also has the same 5 carbon sequence as ribose sugar but loses an oxygen atom. Its chemical formula is H−(C=O)−(CH2)−(CHOH)3−H. In fact, it consists of the sugar currant.

Deoxyribose is an important component of the building blocks of DNA and DNA molecules. It has an aldehyde group (CHO) that interacts with the molecule. Therefore, there is also an aldopentose.

The structures of ribose and deoxyribose are almost identical. Both are simple sugars, but the molecular structure of deoxyribose is missing one oxygen atom.

It plays an important role in forming the base of DNA to form a double-helix structure. These double strands of DNA are the most important components of the chromosome in the cell nucleus.

Difference Between Deoxyribose And Ribose



Chemical formula



IUPAC name




It has a hydrogen (H) atom at position 2

It has a hydroxyl (OH) group at position 2

Molar mass

134.13 g/mol

150.13 g/mol

Also known as




1929 by Phoebus Levene

1891 by Emil Fischer and Oskar Piloty

Found in




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