Difference Between Primary Lymphoid Organs and Secondary Lymphoid Organs

Definition of Introduction – Lymphoid Organs

The human body contains a liquid called lymph, which is used to clean and filter the fluid between the small lymphatic vessels throughout the body and then transport it through the lymphatic vessels to eventually reach the lymph nodes. Within that system are primary lymphatics and secondary lymphatics.

Lymphoid organs can be defined as the site of growth and development of lymphocytes and other immune cells.

Difference Between Primary Lymphoid Organs and Secondary Lymphoid Organs?

These primary and secondary components perform many important functions for the immune system. Read on to analyze their work and find out how they differ from each other.

Primary Lymphoid Organs

  • The function of primary lymphoid organs is the production and maturation of lymphocytes
  • It is also the location where stem cells differentiate and mature into B and T cells
  • Humans have two primary lymphatic organs – the thymus gland and the red bone marrow
  • B and T cells are formed in the bone marrow

Secondary Lymphoid Organs

  • Secondary lymphoid organs serve as a sort of “monitoring station” for the contents of the extracellular fluids – such as the blood, lymph and tissue fluid.
  • It is also the location where the lymphocytes are activated.
  • Examples of secondary lymphoid organs include the spleen, tonsils, lymph nodes, and Peyer’s patches.

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